60 Indications for and Consequences of Intrauterine Transfusions
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PLASMA AND ALBUMIN TRANSFUSIONS: INDICATIONS AND CONTROVERSIES Page 1 PLASMA AND ALBUMIN TRANSFUSIONS: INDICATIONS AND CONTROVERSIES
Albumin plays an important role in health and disease. Albumin is a major contributor to colloid oncotic pressure (COP), binds endogenous and exogenous molecules, mediates coagulation, and helps to maintain normal microvascular permeability. The clinical consequences of hypoalbuminemia reflect these varied functions. Significant hypoalbuminemia contributes to increased morbidity and mortality. ...
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A reevaluation of the indications for and alternatives to transfusion of allogeneic blood was precipitated by transfusion-induced HIV. The transfusion trigger has shifted from an optimal hemoglobin level and hematocrit (10/30) to that level of hemoglobin necessary to meet the patient's tissue oxygen demands. This critical level can best be determined by physiologic measurements. A number of aut...
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Intrauterine transfusion (IUT) therapy is the treatment of choice in severe hemolytic disease of the fetus. This treatment automatically implies the introduction of alloantigens in the fetal circulation, which might potentially influence the unprimed fetal immune system. The present study provides evidence that the fetal immune system is indeed prone to modulations of the T-cell receptor BV (TC...
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For more than 40 years now, platelet transfusion has provided life-saving supportive therapy to hematological patients with impaired hematopoiesis, bone marrow aplasia induced by chemotherapy, surgical patients and patients with a variety of disorders of platelet count and function. More than 2.9 million platelet components are transfused each year in Europe and 57000 in Croatia. Patients with ...
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RATIONALE Plasma transfusions are frequently prescribed for critically ill children, although their indications lack a strong evidence base. Plasma transfusions are largely driven by physician conceptions of need, and these are poorly documented in pediatric intensive care patients. OBJECTIVES To identify patient characteristics and to characterize indications leading to plasma transfusions i...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1967
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-196705000-00067